Users Stopping Slimming Jabs Put On Weight at a Quadrupled Rate Compared to People Using Diet and Exercise

Fresh analysis suggests that people who discontinue popular slimming jabs like Mounjaro or Wegovy may regain lost weight far faster than those who stop traditional lifestyle regimens.

Findings released in a major medical journal shows that while obese individuals can lose substantial amounts of their body weight while using the jabs, the weight is regained at an average rate of 0.8 kg per month once they quit.

"People purchasing such drugs should be aware of the danger of quick weight regain when the treatment is stopped," stated lead investigator Dr. Susan Jebb.

That rate of recovery suggests a reversion to original weight within about 18 months.

Weighing Approaches

The research, which reviewed dozens of studies involving over 9,000 of participants, compared the results of these new drugs with conventional dieting.

The team emphasize that individuals who shed pounds through lifestyle changes alone typically see a less rapid creep back—around 0.1 kg a month—after stopping.

Explaining the Quick Rebound

Experts believe the mode of action of the injections accounts for the heightened weight return.

These medications copy a body's own chemical called GLP-1, which helps regulate feelings of fullness.

"Long-term administration of GLP-1 levels far above than normal might result in the body to produce less of its own natural GLP-1, and could reduce responsiveness to its effects," said Dr. Adam Collins, a dietetics researcher.

"Withdrawal of this medication means appetite is no longer kept in check, making binge eating much more probable."

A Lifelong Issue?

Medical guidelines recommend the jabs for people with obesity-related medical conditions, accompanied by recommended lifestyle changes.

Many experts argue that, considering the high risk of relapse, the therapy is often ongoing.

This opinion is reinforced by drug manufacturers, who say that the results "underscore the long-term character of obesity," akin to managing conditions like diabetes.

User Experiences

People who have discontinued the jabs describe a intense resurgence of appetite.

"It was like a switch activating and you're instantly starving," recalled one woman.

The struggle is exacerbated if individuals have not established lasting lifestyle or habit changes during therapy.

Significant Adoption

Recent estimates suggest that a significant number of adults in the UK have used these injections in the past year, with desire continuing to grow.

• Use is more common among women compared to males.
• The middle-aged age group shows the highest level of interest.
• Many obtain the medications through private prescriptions rather than public health services.

Ultimately, clinicians caution that while these medications are potent tools for shedding pounds, they are not a permanent solution and maintained weight loss relies on ongoing lifestyle support.